消化性溃疡病人巨细胞病毒感染的研究

A STUDY OF CYTOMEGALOVIRUS INFECTION PATIENTS WITH PEPTIC ULCER

采用高敏性的酶连接免疫吸附测定法检测了34例消化性溃疡病人血清特异HCMV-IgM和HCMV-IgA,结果表明,消化性溃疡病人活动性HCMV感染率(IgM/IgA)为41.17%,而对照组为4.00%,两者之间有显著性差异(P<0.01)。胃溃疡和十二指肠溃疡病人活动性HCMV感染率之间无差异(P>0.05)。本文还对人巨细胞病毒感染与消化性溃疡发病的关系及其发病机理进行了初步探讨。

IgM and IgA antibodies against cytomegalovirus (CMV) were examined in the serum from 34 patients with peptic ulcer by using ELISA. Active cytomegalovirus infec- tionwas found in 41.17% of the patients but only in 4.00% of normal subjects (P< 0.01). The difference in active cytomegalovirus infection rate was not significant be- tween patients with gastric ulcer and those with duodenal ulcer (P>0.05). Nor was any significant difference found between male and female patients.