^(89)Srcl_2对骨转移癌的治疗应用

Application of ^(89)Src1_2 to treat metastasis of the bone in malignancy

目的探讨89Srcl2对恶性肿瘤骨转移的治疗效果。方法对52例骨转移癌病人两次静脉注射89Srcl2治疗,每次2.2MBq/kg,两次治疗间隔时间为3月。结果第1次治疗骨痛缓解率为69.23%,两次治疗后缓解率为86.54%;第1次89Srcl2治疗后对骨转移癌有效率为26.9%,第2次治疗后有效率为42.3%。结论89Srcl2不仅可以缓解骨转移癌所致的骨痛,而且对转移灶也有一定的治疗作用,连续两次治疗更为有效。

Objective To study the effect of 89 Srcl 2 in treatment of metastasis of the bone in malignancy.Methods 52cases are treated by means of injection of 89 Src1 2 (2.2MBq/kg)twice in a three month interval.Results The effective rat of the bone-pain palliated was69.23%after the first treatment and86.54%after the second treatment.The effective rate of the metastasis of the bone was26.9%after the first treatment and42.3%after the second treatment.Conclusions The 89 Src1 2 b is effective on cancer patients with metastasis and bone pain,and twice treatment is better than single treatment.