纳络酮治疗椎-基底动脉供血不足

Treatment of Vertebral Basilar Artery BloodInsufficiency by Naloxon

目的 研究纳络酮对椎 -基底动脉供血不足的治疗作用。方法 选择 114例椎 -基底动脉供血不足的患者 ,随机分为对照组和治疗组 ,前者用复方丹参、维脑路通治疗 ,后者加用纳络酮。观察患者症状缓解情况、药物起效时间及不同剂量的作用差异。结果 纳络酮治疗组的症状缓解率高 ,药物起效时间快 ,大剂量组较小剂量组作用更显著。无明显不良反应。结论 纳络酮治疗椎 -基底动脉供血不足疗效显著 ,安全性好。

Objective To explore the role of naloxon in treating vertebral-basilar artery blood insufficiency.Methods 114 patients with vertebral-basilar artery blood insufficiency were divided into two groups randomly. Control group were treated with danshen and troxerutin, the treatment group were treated with naloxone beside danshen and troxerutin.Remission of symptoms, the time of drug effects appearing and difference in drug effects of diffentent drug dosage were observed.Results Remission rate of group treated with naloxone was higher, the time of drug effects appeared more fastly and the curative effect of large dose group was more significant than that of small dose group.There were no serious side-effects.Conclusion The curative effect of naloxone in treating vertebral-basilar artery blood insufficiency is significant and the safety of naloxone is good.