摘要
以水合肼与顺丁烯二酸酐为起始原料,经扩环、氯化、缩合三步反应制备磺胺氯哒嗪钠。采用正交设计法筛选出合 成二羟基哒嗪的最优化条件,收率达92.4％。
Sulfachlorpyridazine sodium was synthezed from hydrazine hydrafe and maleic anhydride through three feet.The first was to syntheze 3,6-dihydroxypyridazine,its yield was 92.4%.
出处
《河北化工》
2004年第6期46-47,共2页
Hebei Chemical Industry
关键词
磺胺氯哒嗪钠
合成
正交设计
二羟基哒嗪
sulfachlorpyridazine sodium
synthesis
orthogonal design
3,6-dihydroxypyridazine
