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γ-GCS和慢性阻塞性肺疾病 被引量:6

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摘要 氧化 /抗氧化失衡是COPD主要发病机制之一 ,谷胱甘肽 (GSH)是细胞内重要的抗氧化剂 ,对维持肺上皮细胞完整和抗氧化损伤起关键作用。γ 谷氨酰半胱氨酸合成酶 (γ GCS )是GSH合成的限速酶 ,调节细胞内GSH水平。γ GCS活性及基因表达对COPD均有重要意义。
机构地区 湖南省老年医院
出处 《国外医学(呼吸系统分册)》 2004年第6期391-394,共4页 Section of Respiratory System Foreign Medical Sciences
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