西藏麝香合成新工艺

A new Process for Synthesis of Musk Tibetene

以催化重整C9芳烃分离装置分离出均三甲苯、偏三甲苯后的副产品重组分溶剂(169～178℃馏分)—混合C9芳烃为原料,其中含连三甲苯40%～50%,以三氯化铝为催化剂与异丁烯进行烷基化反应,合成出5 叔丁基 1,2,3 三甲基苯中间体,经蒸馏后,用混酸进行硝化反应得到西藏麝香。本方法不但具有工艺路线简单,生产成本低的特点,同时也解决了富集连三甲苯的利用问题。

In this process , the heavy fraction solvent (169～178℃)— mixed C_(9) aromatic hydrocarbon, namely, the by-product of mesitylene and pseudocumene which were separated from C_(9) aromatic hydrocarbon catalytic reforming separation facility , will be the feedstock which was alkylated by isobutene in presence of aluminium trichloride as catalyst to synthesize 5-tert-butyl-1,2,3 trimethyl benzene intermediate product which , after distillation ,was nitrated with nitro-sulfuric acid to obtain Musk Tibetene. This method is low cost and simple in design , and the pregnant hemimellitene is fully used in this process.