摘要
血小板在心血管疾病的发生发展中起关键作用。运动对血小板功能的影响是双向的。短时间剧烈运动活化血小板 ,而规则有氧运动抑制血小板。运动诱导血小板活化的机制有多种 ,其中主要可能是运动诱导产生的儿茶酚胺通过肾上腺素能受体 (α2 -AR)发挥生物学效应。运动抑制血小板功能极有可能是通过内源性一氧化氮 (NO)的释放增多 ,引起血小板内环磷酸鸟苷 (cGMP)
Platelets play a critical role in pathogenesis and procession of cardiovascular diseases.The effect of exercise on platelet function is two?way.Strenous,acute exercise activates platelets whereas regular,aerobic exercise suppresses platelet function.Platelet activation during exercise may be related to several mechanisms,the most possibility is that exercise?increased catecholamine exerts biological influence via adrenergic receptors(α 2?AR).Exercise may suppress platelet function through the increase in endogenous NO and the elevation of guanosine 3,5?cycli?monophsphate(cGMP)content in platelets.
出处
《浙江体育科学》
北大核心
2000年第6期38-41,46,共5页
Zhejiang Sport Science
