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骨髓源性肝干细胞的研究进展

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摘要 骨髓干细胞的横向分化/转分化是近年来研究的热点,骨髓源性肝干细胞是在一定条件下能向肝细胞横向分化/转分化的骨髓干细胞,他的发现为肝病治疗带来了新的希望.近年来对骨髓源性肝干细胞的分化机制、分化环境及条件、分离和培养的研究进一步深入,使其在细胞移植、基因治疗等方面有广阔的前景.现就骨髓源性肝干细胞的研究进展及其在临床治疗中应用前景综述如下.
出处 《世界华人消化杂志》 CAS 2004年第10期2435-2437,共3页 World Chinese Journal of Digestology
基金 四川省教育厅资助课题 No.2003-A027
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参考文献28

  • 1Petersen BE, Bowen WC, Patrene KD, Mars WM, Sullivan AK,Murase N, Boggs SS, Greenberger JS, Goff JP. Bone marrow as a potential source of hepatic oval cells. Science 1999;284:1168-1170.
  • 2Theise ND, Badve S, Saxena R, Henegariu O, Sell S, Crawford JM, Krause DS. Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation. Hepatology 2000;31:235-240.
  • 3Theise ND, Nimmakayalu M, Gardner R, Illei PB, Morgan G,Teperman L, Henegariu O, Krause DS. Liver from bone marrow in humans. Hepatology 2000;32:11-16.
  • 4Oh SH, Miyazaki M, Kouchi H, Inoue Y, Sakaguchi M, Tsuji T, Shima N, Higashio K, Namba M. Hepatocyte growth factor induces differentiation of adult rat bone marrow cells into a hepatocyte lineage in vitro. Bioch Bioph Res Commun 2000;279:500-504.
  • 5Miyazaki M, Akiyama I, Sakaguchi M, Nakashima E, Okada M, Kataoka K, Huh NH. Improved conditions to induce hepatocytes from rat bone marrow cells in culture. Biochem Biophys Res Commun 2002;298:24-30.
  • 6Fiegel HC, Lioznov MV, Cortes-Dericks L, Lange C, Kluth D,Fehse B, Zander AR. Liver-specific gene expression in cultured human hematopoietic stem cells. Stem Cells 2003;21:98-104.
  • 7Lagasse E, Connors H, Al-Dhalimy M, Reitsma M, Dohse M,Osborne L, Wang X, Finegold M, Weissman IL, Grompe M.Purified hematopoietic stem cells can differentiate into hepatocytes in vivo. Nat Med 2000;6:1229-1234.
  • 8Almeida-Porada G, Porada CD, Tran N, Zanjani ED. Cotransplantation of human stromal cell progenitors into preimmune fetal sheep results in early appearance of human donor cells in circulation and boosts cell levels in bone marrow at later time points after transplantation. Blood 2000;95:3620-3627.
  • 9Davies JC, Potter M, Bush A, Rosenthal M, Geddes DM,Alton EW. Bone marrow stem cells do not repopulate the healthy upper respiratory tract. Pediatr Pulmonol 2002;34:251-256.
  • 10Ferrari G, Cusella-De Angelis G, Coletta M, Paolucci E,Stornaiuolo A, Cossu G, Mavilio F. Muscle regeneration by bone marrow-derived myogenic progenitors. Science 1998;279:1528-1530.

二级参考文献84

  • 1孙自勤,权启镇,于峻基.转化生长因子β_1(TGF-β_1)与肝纤维化[J].临床肝胆病杂志,1993,9(4):184-186. 被引量:11
  • 2叶晟 冯懿正 等.P53,P21,NM23和PCNA在原发性肝癌中的表达与预后的关系[J].世界华人消化杂志,1999,7:160-160.
  • 3[1]Vessey CJ,de-la-HallPM. Hepatic stem cells: areview. Pathology 2001;33:130-141
  • 4[2]Akison MR, GoldingM, Sarraf CE. Liver stem cells:when the going get though they get going. Int J Exp Pathol 1997; 78:365-381
  • 5[3]Strain AJ, Crosby HA. Hepatic stem cells. Gut 2000; 46:743-745
  • 6[4]Alison M, Sarraf C. Hepatic stem cells. J Hepatol 1998; 29:676-682
  • 7[5]Toshihior M. Hepatic stem cells:form brone marrow cells to hepaticytes. Biochem Biophy Res Commun 2001 ;281:1-5
  • 8[6]Xiao JC, Ruck P, Kaiserling E. Small epithelial cells in extrahepatie biliary atresia:electron mieroseopic and immunoelectron microscopic findings suggest a close relationship to liver progenitor cells. Histopathology 1999; 35:454-460
  • 9[7]Theine ND, Saxena R, Portmann BC, Thung SN, Yee H, Chiriboga L, Kumar A,Crawford JM. The canals of Hering and hepatic sten cells in humans. Hepatology 1999;30:1425-1433
  • 10[8]Golding M, SarrafC, Lalani EN, AlisonMR. Reactive biliary epithelium: the product of a pluripotential stem cell compartment? Hum Pathol 1996: 27:872-884

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