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Survivin在非小细胞肺癌中表达的初步研究 被引量:1

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摘要 目的 :探讨survivin基因在非小细胞肺癌 (non smallcelllungcancer,NSCLC)中的表达情况 ,为survivin基因用于NSCLC诊断以及治疗提供理论依据。方法 :用RT PCR法检测正常细胞株、肺癌细胞株、非小细胞肺癌活体标本以及癌旁组织 ,比较survivin基因的表达情况。结果 :正常细胞株以及癌旁组织中未检测出survivin表达 ,肺癌细胞株以及肺癌活体标本有高表达。结论 :survivin可能作为非小细胞肺癌的检测以及治疗新靶点。
出处 《实用医学杂志》 CAS 2004年第12期1348-1350,共3页 The Journal of Practical Medicine
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同被引文献6

  • 1周莉,金克炜,张天宝.云锡矿粉诱导永生化人支气管上皮细胞BEAS-2B恶性转化[J].癌变.畸变.突变,2006,18(5):367-369. 被引量:7
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  • 6Tamm I,Wang Y,Sausville E,et al.TAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas(CD95),Bax,caspases,and anticancer drugs[J].Cancer Res,1998,58(23):5315-5320.

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