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Cleavage of DNA by a New Mixed-ligand Cu(Ⅱ) Complex

Cleavage of DNA by a New Mixed-ligand Cu(Ⅱ) Complex
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摘要 Cleavage of DNA pUC19 by [Cu(saldien)(NH3)]Cl2 (here, saldien=bis(salicylicdene)- diethylenetriamine) was investigated at different pHs, times, concentrations, and 37℃. It was found that the copper(Ⅱ) complex could cleave DNA without added coreactants. Cleavage of DNA pUC19 by [Cu(saldien)(NH3)]Cl2 (here, saldien=bis(salicylicdene)- diethylenetriamine) was investigated at different pHs, times, concentrations, and 37℃. It was found that the copper(Ⅱ) complex could cleave DNA without added coreactants.
作者 QingHuaZHOU PinYANG
机构地区 InstituteofMolecularScience
出处 《Chinese Chemical Letters》 SCIE CAS CSCD 2005年第1期81-84,共4页 中国化学快报（英文版）
基金 support of the National Natural Science Foundation of China(No:20171031) the Shanxi Provincial Natural Science Foundauon for Youth(No:20011007)
关键词 Copper(Ⅱ) complex cleavage of DNA saldien. Copper(Ⅱ) complex, cleavage of DNA, saldien.
分类号 Q523 [生物学—生物化学]
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参考文献12

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Chinese Chemical Letters
2005年 第1期

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