摘要
铅可通过多种途径进入细胞内,干扰细胞的正常生理代谢,产生细胞毒性作用。该文就近年来用Fura2、Indo1等荧光指示剂检测铅对细胞的毒性作用作以综述。
There are different conclusions about cytotoxicity of lead(Pb 2+ ) becouse of different detecting methods. Several studies indicated that Pb 2+ enters the into cells by many approaches, and disturbs normal physiological metabolism of the cells. Other reports demonstrated that the cytotoxicity effect of Pb 2+ is due to that it can disturb ionic channels on the membrane. This paper reviewed recent studies on cytotoxicity of Pb2 by detecting fluorescence indicators such as Fura2, Indo 1.
出处
《国外医学(妇幼保健分册)》
2004年第6期332-333,共2页
Foreign Medical Sciences (Section of Maternal and Child Health)
关键词
铅
荧光指示荆
细胞毒性
lead
fluorescence indicator
cytotoxicity