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葡萄糖水溶液浓度的近红外光谱测量法——人体血糖浓度无创伤测量方法基础研究 被引量:10

NEAR—INFRARED SPECTROSCOPIC MEASUREMENT OF GLUCOSE CONCENTRATIONS IN AN AQUEOUS MATRIX ——FUNDAMENTAL STUDY ON NONINVASIVE MEASUREMENT METHOD OF HUMAN BLOOD GLUCOSE CONCENTRATION
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摘要 本系统研究了近红外光谱技术与化学计量学理论相结合测定水溶液中葡萄糖浓度的方法。讨论了偏最小二乘法 (PLS)校正模型中光谱范围的优化选择 ,同时也讨论了仪器精度、测量方法与测量精度之间的传递函数 ,给出实现预期测量精度的必要条件。葡萄糖浓度的均方根预测误差 (RMSEP)为 4 .13mg/dL ,浓度测量值与参考值具有良好的相关性 (相关系数为 0 .998)。实验结果表明 :近红外光谱分析方法能够达到一定精度 (RMSEP <5mg/dL) ,具有进一步研究价值。 No abstract available
出处 《中国生物医学工程学报》 EI CAS CSCD 北大核心 2004年第6期602-606,561,共6页 Chinese Journal of Biomedical Engineering
基金 国家自然科学基金资助项目 (No .3 0 170 2 61) 国家十五科技攻关项目 (N0 .2 0 0 1BA70 6B -2 1)
关键词 血糖浓度 无创伤检测 测量精度 偏最小二乘法 遗传算法 Blood glucose concentration Noninvasive measurement Prediction accuracy Partial least-squares Genetic algorithms
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