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新型糠醛缩氨基硫脲衍生物的合成及其抑菌活性的研究

SYNTHESIS AND BACTERIOSTATIC ACTIVITY OF FURFURAL THIOSEMICARBAZONE DERIVATIVES
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摘要 设计合成了4种新型糠醛缩氨基硫脲衍生物,化学结构经红外光谱和元素分析证实。抑菌活性测试表明,含有硝基基团的化合物C_1和C_3活性较好,其中C_3活性最高。 In order to search out ideal bactericides and fungicides,4 of furfural thiosemicarbazone derivatives have been synthesized and tested for bacteriostatic and fungistatic activity.The structures of these compounds have been elucidated on the basis of elemental analysis and I.R.spectra. The relation of the structure-activity is discussed.The results showed that the activity of compound C3(N^4-methyl-5-nitrofurfural thiosemicarbazone) is the highest.
出处 《山东医科大学学报》 1993年第4期351-353,共3页 Acta Academiae Medicinae Shandong
关键词 缩氨硫脲 硝基糠醛 抑菌 合成 Thiosemicarbazones 5-Nitrofurfural Antibacterial
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