黑素细胞黑皮素-1受体介导的信号转导机制
摘要
黑素细胞的膜表面黑皮素-1受体与配体结合后,通过一系列的信号转导,促进黑素生成酶的生成、调节肌动蛋白拆卸和组装,具有促进黑素细胞黑素形成和树突形成的作用,文中就这两种作用产生过程中的信号转导作一综述。
出处
《国外医学（皮肤性病学分册）》
2005年第1期53-55,共3页
Foreign Medical Sciences(Section of Dermatology and Venereology)
参考文献46
-
1Roesler WJ, Park EA, McFie PJ. Characterization of CCAAT/enhancer-binding protein alpha as a cyclic AMP-responsive nuclear regulator. J Biol Chem, 1998,273 : 14950 - 14957.
-
2Bertolotto C, Busca R, Abbe P, et al. Different cis-acting elements are involved in the regulation of TRP1 and TRP2 promoter activities by cyclic AMP: pivotal role of M boxes (GTCATGTGCT) and of microphthalmia. Mol Cell Biol, 1998,18:694 - 702.
-
3Hodgkinson CA, Moore K J, Nakayama A, et al. Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein. Cell, 1993,74:395 - 404.
-
4Tachibana M, Perez-Jurado LA, Nakayama A, et al. Cloning of MITF, the human homolog of the mouse microphthalmia gene and assignment to chromosome 3p14.1 - p12.3. Hum Mol Genet, 1994,3 :553 - 557.
-
5Bertolotto C, Abbe P, Hemesath TJ, et al. Microphthalmia gene product as a signal transducer in cAMP-induced differentiation of melanocytes. J Cell Biol, 1998,142 : 827 - 835.
-
6Shibahara S, Yasumoto K, Amae S, et al. Regulation of pigment cellspecific gene expression by MITF. Pigment Cell Res, 2000,13:98 - 102
-
7Yang YK, Ollmann MM, Wilson BD, et al. Effects of recombinant agouti-signaling protein on melanocortin action. Mol Endocrinol,1997,11:274 -280.
-
8Furumura M, Sakai C, Potterf SB, et al. Characterization of genes modulated during pheomelanogenesis using differential display. Proc Natl Acad Sci U S A, 1998,95:7374- 7378.
-
9Furumura M, Potterf SB, Toyofuku K, et al. Involvement of ITF2 in the transcriptional regulation of melanogenic genes. J Biol Chem,2001, 276:28147-28154.
-
10Kimura K, Hattori S, Kabuyama Y, et al. Neurite outgrowth of PC12 cells is suppressed by wortmannin, a specific inhibitor of phosphatidylinositol 3 - kinase. J Biol Chem, 1994, 269 : 18961 - 18967.
-
1沈丹蓓,夏隆庆.黑素细胞黑皮素-1受体[J].国外医学（皮肤性病学分册）,2002,28(5):310-312.
-
2薛春雨,李蠡,邢新.黑皮素-1受体对皮肤色素的调控作用[J].中国美容医学,2003,12(5):542-544. 被引量：2
-
3吕川,戴海英,张敬德,王晓芸.黑皮素-1受体在瘢痕疙瘩中的表达及基因沉默黑皮素-1受体对成纤维细胞增殖的影响[J].组织工程与重建外科杂志,2011,7(3):147-150. 被引量：2
-
4倪俊.选择素与创伤、脓毒症[J].国外医学（创伤与外科基本问题分册）,1998,19(3):133-136. 被引量：7
-
5王震英,张莉.表皮生长因子受体及相关皮肤病[J].国外医学（皮肤性病学分册）,2003,29(2):94-96. 被引量：1
-
6李洪武,朱文元,夏明玉,谭诚.中药赤菟酊治疗白癜风临床疗效观察[J].中国麻风皮肤病杂志,2006,22(1):62-63. 被引量：16
-
7卢宁,赵小东,刘玉峰,高天文.黑素小体转运的研究进展[J].中国美容医学,2004,13(1):101-103. 被引量：1
-
8李菲,赵广.皮肤色素沉着与受体[J].中国皮肤性病学杂志,2008,22(11):690-693. 被引量：2
-
9王骏骅,赵建宁.人工关节假体植入后骨溶解的研究进展[J].中国骨伤,2003,16(7):443-445.
-
10郑锦芬,李建军,江智茂,叶蓉,胡小平,陈办成.内皮素-1对培养的黑素细胞生物学特性的影响[J].中国麻风皮肤病杂志,2008,24(11):871-873.
