精液抗精子抗体与衣原体、支原体感染关系

Relationship between sperm antibody and chlamydia trachomatis and ureplasma urealyticum infections

目的了解不育症患者精液抗精子抗体(AsAb)与解脲支原体(UU)、沙眼衣原体(CT)感染的关系及其与年龄、婚龄、抗感染治疗后的关系,进一步探讨不育的致病因素,提高诊断的准确率和治愈率。方法收集94例CT及UU感染的不育病例与62例无感染的正常生育男子,用MAR法(混合抗球蛋白反应试验,Mixedantiglobulinreactiontest)进行精液抗精子抗体检测。结果不育感染组和正常生育组的AsAb检测结果表明,不育感染组的阳性率为35.1%,明显高于对照组4.8%,差异有显著性意义(P<0.01),抗感染治疗后,AsAb9例转阴,感染者婚龄越长,精液AsAb阳性率越高,治疗后转阴率越低。结论支原体、衣原体感染与AsAb关系非常密切,是引起男性免疫性不育的一个重要因素。

Objective To study the relationship between sperm antibody and chlamydia trachomatis and ure-plasma urealyticum infections and age group,marrige of years,changes after antiinfection in infertile males,so that to asscss the causal factors in infertility and try to confirm the etiology and increase the detection and cure rate.Methods Sperm antibody in94male infertility patients with CT and UU infections and62normal productive men were tested by Mixed antiglobulin reaction test.Results The AsAb in CT and UU positive and normal groups were35.1%,4.8%,the differences between CT/UU positive and normal groups were significant(P<0.01),after antiinfection,9AaAb positive patiebts became negative,the longer the marrige of years were,the higher the sperm antibody positive rate were,to become negative was lower after treat.Conclusions There was very close relationship between sperm antibody and chlamydia trachomatis and ureplasma urealyticum infections,it was an important factor in male immune infertility.