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冠心病患者外周血中炎性细胞水平的临床观察

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摘要 目的探讨外周血中白细胞及其分类中的中性粒细胞和单核细胞水平与冠心病的发生、发展中的相关性。方法423例患者根据冠状动脉造影情况分冠心病组和冠脉正常组(对照组),冠心病组根据冠脉病变程度和临床特点又分两对亚组,为冠脉病变重度组和轻度组,急性冠脉病变组和稳定性心绞痛组。冠心病组和对照组分别测定外周血白细胞、单核细胞和中性粒细胞水平,采用统计学方法对各组之间进行对比。结果冠心病组及其亚组冠脉病变重度组和急性冠脉病变组白细胞水平明显高于对照组(P<0.001),急性冠脉病变组中性粒细胞水平明显高于对照组和稳定性心绞痛组(P<0.001),单核细胞水平各组均高于对照组(P<0.05)其中冠心病组及其亚组稳定性心绞痛组和冠脉病变重度组尤其显著。结论冠心病的发生、发展与炎性细胞有相关性,急性冠脉病变与中性粒细胞水平有相关性,冠脉病变严重程度和稳定性心胶痛与单核细胞有相关性。
出处 《海南医学》 CAS 2005年第2期83-84,共2页 Hainan Medical Journal
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