三种治疗消化性溃疡及根除幽门螺杆菌方案的成本——效果分析

Cost-effectiveness analysis of three therapeutic-schemes for treating peptic ulcer and eradicating Helicobacter pylori

目的探讨不同药物治疗方案对同一疾病所产生的经济效果。方法将102例消化性溃疡患者,随机分为3组,A组方案为三九胃泰+雷尼替丁+阿莫西林+甲硝唑;B组方案为枸橼酸钾+雷尼替丁+阿莫西林+甲硝唑;C组方案为雷尼替丁+阿莫西林+甲硝唑。运用药物经济学的成本—效果分析方法进行评价。结果B组方案成本—效果比较低,有效率高。结论B组方案为最佳方案。

Objective To discuss the economic effects of different therapeutic schemes for treating the same illness. Methods One hundred and two cases of peptic ulcer were collected from literature and were randomly divided into three groups receiving different medications: scheme A: sanjiuweitai 2.5 g+ranitidine 150 mg+amoxicillin 500 mg+metronidazole 400 mg, twice daily; scheme B: lizhudele 220 mg+ranitidine 150 mg+amoxicillin 500 mg+metronidazole 400 mg, twice daily; scheme C: ranitidine 150 mg+amoxicillin 500 mg+metronidazole 400 mg, twice daily. The data were evaluated with cost-effectiveness analysis. Results Scheme B had the lowest cost-effectiveness ratio with the highest effective rate. Conclusion Scheme B is the best one.