千里光保肝作用的实验研究

Study of Protective Effect of Senecio Scandens Bush - Ham on Chemical Liver Injury

本试验用四氯化碳建立小鼠肝损伤模型,以联苯双酯为阳性对照,对不同剂量的千里光进行保肝作用研究,对小鼠采血测定血清ALT、AST等生化指标,取肝脏计算肝脏指数,作组织病理学观察。结果发现千里光能显著降低血清ALT、AST的升高;抑制肝脏组织病理学改变,保护肝功能。

The study of protective effect of Senecio Scandens Buch - Ham (SSBH) on carbon tetrachloride inducing mice liver injury was reported in this paper. SSBH was tested by three different doses, biphenyl dicarboxylate was used as positive control. The blood of mice was collected to assay ALT and AST in serum, the liver was taken to calculate the liver index and make histological slide. The result demonstrated that SSBH could reduce the level of ALT and AST in serum and inhibit the liver injury.