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湿热安胶囊治疗湿热蕴脾证的临床及实验研究

Clinical and Experimental Studies on Treatment of the Pattern of Dampness-heat Brewing in the Spleen with ShiReAn Capsule
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摘要 目的:探讨湿热安胶囊治疗湿热蕴脾证的疗效和机制。方法:选择90例湿热蕴脾证患者,随机分为治疗组(用湿热安胶囊,每日3次),对照组(胃复安,每日3次),观察其各症状及体征等方面的变化,进行胃肠运动,止泻,利尿等动物实验。结果:治疗组在疗效、症状、体征等方面均明显优于对照组(P<0.05或P<0.01),且湿热安胶囊对胃肠运动具有双向调节作用,止泻和利尿的作用。结论:湿热安胶囊对湿热蕴脾证有良好的治疗效果。 Objective: To study the effect and mechanism of ShiReAn (SRA) capsule, a Chinese pattern medicine. Method: Firstly we selected 90 patients belonging to the pattern of Dampness-heat brewing in the spleen, a disease of Traditional Chinese Medicine. Then we divided them into two groups randomly. The treated group were treated with SKA capsules, three time per day. And the control group were treated with Metclopramide tablets. The changs in symptoms and signs after treatment were observed. Animal experimental studies on gastrointestinal activity, antidiarrheal effect and diuretic effect were alse conducted. Results; The curative effect in the treated group was higher than that in the control group. The improvement of symptoms and signs in the former was also better than that in the latter (P<0.01 or P<0.05). Animal experimental studies showed that SRA capsule has both-way adjustment effect on the gastrointestinal activity, also it has antidiarrheal and diuretic effects. The animal long-term toxicity test showed that SRA capsule was non-toxic. Conclusion: SRA capsule has a good curative effect in treating the pattern of dampness-heat brewiy in theh spleen.
出处 《四川生理科学杂志》 2000年第1期32-37,共6页 Sichuan Journal of Physiological Sciences
基金 四川省科委资助重点科技项目(川卫科教发 1997055)
关键词 治疗组 胶囊 湿热蕴脾证 对照组 利尿 胃肠运动 体征 结论 目的 变化 the pattern of dampness-heat brewiny in the spleen ShiReAn (SRA) capsule gestrointestinal activity antidiarrheal diuretic test
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参考文献1

  • 1[4]李仅奎主编.《中药药理实验方法学》.上海科学技术出版社,1991

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