抗急性髓系白血病M_2型单克隆抗体1D_1特异性的观察

OBSERVATION OF SPECIFICITY OF MONOCLONAL ANTIBODY—1D_1 IN ACUTE MYELOID LEUKEMIA—M_2 TYPE

应用长春生物制品研究所提供的抗急性髓系白血病(AML)—M_2型单克隆抗体1D_1与10例AML—M_2型及40例其他类型白血病细胞反应。结果表明:1D_1抗体与M_2型白血病有特异性反应,与其他类型白血病无明显的交义反应,说明1D_1抗体具有很好的特异性。

We used monoclonal antibody(McAb)of anti—acute myeloid leukemia—m_2 type from Changchun Institute of Biologicalproducts to test 10 cases of M_2 types and 40 cases of other types of Ieukemias.ID McAb gave markedly positive reaction with m_2 type leukemia cells,but other type of leukemia cells waere no signficant reaction,we found the ID McAb was a(?)specific McAb of anti—acute myeloid leukemia—M_2 type.