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氯吡格雷在缺血性心脏病中的应用 被引量：14

Role of Clopidogrel in Ischemic Heart Disease
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摘要 缺血性心脏病是威胁人类生命的主要病因 ,氯吡格雷可显著减少心脏不良事件。 Ischemic heart disease is a major cause threatened to the people all over the world,and clopidogrel may significantly decrease the incidence rate of cardiac adverse events.
作者 王长华 胡大一
机构地区 首都医科大学附属北京同仁医院心脏中心
出处 《心血管病学进展》 CAS 2005年第1期52-55,共4页 Advances in Cardiovascular Diseases
关键词 氯吡格雷 缺血性心脏病 不良事件 病因 威胁 Ischemic heart disease Clopidogrel
分类号 R541.4 [医药卫生—心血管疾病]
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参考文献23

  • 1Savcic M,Hauert J,Bachmann F,et al.Clopidogrel loading dose regimens:kinetic profile of pharmacodynamic response in healthy subjects[J].Semin Thromb Hemost,1999,25(suppl 2):15-19.
  • 2The CURE Investigators.Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation[J].N Engl J Med,2001,345(7):494-502.
  • 3Mehta SR,Yusuf S,Peter RJ,et al.Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention:the PCI-CURE study[J].Lancet,2001,358:527-533.
  • 4Gaspoz JM,Coxson PG,Goldman PA,et al.Cost effectiveness of aspirin,clopidogrel,or both for secondary prevention of coronary artery disease[J].N Engl J Med,2002,346:1800-1806.
  • 5Popma JJ,Ohman ME,Weitz J,et al.Antithrombotic therapy in patients undergoing percutaneous coronary intervention[J].Chest,2001,119( 1):321S-336S.
  • 6Muller C,Buttner HJ,Peterson J,et al.A randomized comparison of clopidogrel and aspirin versus ticlopidine and aspirin after placement of coronary-artery stents[J].Circulation,2000,101:590-593.
  • 7Bertrand ME,Rupprescht HJ,Urban P,et al.Double-blind study of the safety of clopidogrel with and without a loading dose in combination with aspirin compared with ticlopidine in combination with aspirin after coronary stenting.The Clopidogrel Aspirin Stent International Cooperative Study (CLASSICS) [J].Circulation,2000,102:624-629.
  • 8Bhatt DL,Bertrand ME,Berger PB,et al.Meta-analysis of randomized and registry comparisons of ticlopidine with clopidogrel after stenting[J].J Am Coll Cardiol,2002,39(1):9-14.
  • 9Steinhubl SR,Berger PB,Mann Ⅲ JT,et al.For the CREDO Investigators.Early and sustained dual oral antiplatelet therapy following percutaneous coronary intervention:a randomized controlled trial[J].JAMA,2002,288:2411-2420.
  • 10Lowe HC,Oesterle SN,Khachigian LM.Coronary in-stent restenosis:current status and future strategies[J].J Am Coll Cardiol,2002,39(2):183-193.

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心血管病学进展
2005年 第1期

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