肺癌患者术前肺功能与术后并发症的关系

Relationship between preoperative pulmonary function tests and postoperative comlications in patients with lung cancer

目的 :探讨肺癌患者手术切除后发生并发症的危险因素。方法 :将 2 0 0 1～ 2 0 0 4年在我院行肺楔型切除、肺叶切除、两叶切除、全肺切除的 10 4例患者分为 2组 ,Ⅰ组术前FEV1/FVC(一秒率 )≥ 70 % ,Ⅱ组术前FEV1/FVC <70 % ,分析术后并发症与术前肺功能、年龄、血气分析结果、预测的术后FEV1的关系。结果 :对Ⅰ组患者预测的术后FEV1及FEV1%是预测术后并发症的良好指标。对Ⅱ组患者未发现任何因素能预测术后并发症。结论 :对术前FEV1/FVC≥ 70 %的患者 ,预测的术后FEV1及FEV1%是预测术后并发症的良好指标。

Objective:To explore the risk factor of the postoperative complication after lung cancer resection.Methods:One hundred and four patients who underwent wedge resection(s),lobectomy,bilobectomy or pneumonectomy from 2001 to 2004 were divided into two groups:groupⅠ,with FEV 1/FVC greater than or equal to 70%,and group Ⅱ,with FEV1/FVC less than 70%.Complication rates were analyzed according to preoperative pulmonary variables,age,blood gas analysis,and predicted postoperative FEV 1 within each group.Results:In groupⅠ,multivariate analysis showed that predicted postoperative FEV 1 and FEV 1% were the significant predictor of complications. In group Ⅱ, no significant predictor was identified.Conclusion:In patients with FEV 1/FVC≥70%, predicted postoperative FEV 1 and FEV 1% are the significant predictor of postoperative complications.