Bmi-1与血液系统恶性疾病
摘要
BMI-1基因产物Bmi-l是Polycomb组蛋白家族成员,调节同源盒基因的转录,对哺乳动物的骨骼、造血及神经发育发挥重要作用。研究证实BMI-1对于造血干细胞自我更新及分化潜能的维持至关重要,并在部分血液系统恶性疾病包括白血病及淋巴瘤的发生和发展中发挥重要作用。
出处
《国外医学（输血及血液学分册）》
2005年第1期18-20,共3页
Foreign Medical Sciences(Section of Blood Transfusion and Heanatology)
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