沿海地区学龄儿童甲状腺肿的调查与病因分析

INVESTIGATION AND ANALYSIS OF ETIOLOGY OF GOITER ON SCHOOL CHILDREN IN THE COASTAL REGION

对山东沿海地区6市县28792例7～13岁儿童(男15033例,女13759例)甲状腺肿进行了调查,并分析其发病原因。调查中共发现甲状腺肿大者527例,其中男191例,女336例。甲状腺肿的发生率为1.83%,男女分别为1.27%和2.44%,女性明显高于男性(P<0.005)。在各年龄组发病率中,女性7～8岁组明显低于其他年龄组(P<0.05),男性各年龄组间无显著差异。527例甲状腺肿大儿童中,单纯性甲状腺肿449例(85.20%),甲状腺腺瘤12例(2.28%),慢性淋巴细胞性甲状腺炎7例(1.33%),3例可能为甲状腺激素合成障碍。另56例病因有待进一步随访观察。

The goiter was investigated among 28792 school children(15033 boys and 13759girls) of 6 coastal cities and counties in Shandong Province.Their ages ranged from 7～13 yetrs.527 cases of goiter were found,the incidence being 1.83%,and was obviou-sly higher in females than in males.(1.27% in boys and 2.44% in girls). Among the females the incidence was lower in the 7～8 age group than in theother groups(P<0.05).There was no significant difference between the differentage groups of the males.Of the 527 cases,449 were simple thyrocele (85.2%),12 thyroiphyma (2.28%) and 7 chronic lymphocytic throiditis (1.33o%).Three casesof goiter perhaps resulted from disorder of thyroxine synthesis.The causes of other56 cases need further inrestigation.