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伐地那非治疗耻骨后前列腺根治切除术后的勃起功能障碍

Vardenafil for the Treatment of Men with Erectile Dysfunction after Radical Retropubic Prostatectomy
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摘要 超过三分之一的患者在行保留性神经的前列腺根治切除术后会出现勃起功能障碍(ED)。最近的研究表明,磷酸二酯酶 5(PDE5)抑制剂伐地那非可改善保留单侧或双侧神经的耻骨后前列腺根治切除术后ED患者的勃起功能,而且安全性良好。 More than one-third of men may experience erectile dysfunction(ED) after nerve-sparing radical retropubic prostatectomy. A recent study has shown that vardenafil, a phosphodiesterase 5 inhibitor, could significantly improve the key indices of erectile function in men after unilateral or bilateral nerve-sparing radical retropubic prostatectomy. Few adverse events were observed in the study.
作者 黄翼然
出处 《中华男科学杂志》 CAS CSCD 2005年第1期76-79,共4页 National Journal of Andrology
关键词 伐地那非 磷酸二酯酶5抑制剂 勃起功能障碍 耻骨后前列腺根治切除术 vardenafil phosphodiesterase 5 inhibitor erectile dysfunction radical retropubic prostatectomy
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参考文献5

  • 1Talcott JA, Rieker P, Propert KJ, et al. Patient-reported impotence and incontinence after nerve-sparing radical prostatectomy[J]. J Nat Cancer Inst, 1997, 89(15): 1117-1123.
  • 2Brock G, Nehra A, Lipschultz L. Influence of vardenafil on erectile dysfunction and depressive symptoms post radical prostatetom[J]. Int J Impot Res, 2002, 14(Suppl 3) : S97.
  • 3Keating GM, Scott LJ. Vardenafil: a review of its use in erectile dysfunction [ J ]. Drugs, 2003, 63 ( 23 ) : 2673-2703.
  • 4Brock G, Nehra A, Lipshultz LI, et al. Safety and efficacy of vardenafil for the treatment of men with erectile dysfunction after radical retropubic prostatectomy [ J ]. J Urol, 2003, 170 (4 Pt1 ) :1278-1283.
  • 5Vezina JG, Nehra A, Brock G, et al. Vardenafil improved patient satisfaction with erection hardness, orgasmic function, and sexual experience in men with erectile dysfunction following nerve-sparing radical prostatectomy [ J ]. J Urol, 2003, 169 ( Suppl 4) : 245.

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