急性缺血性卒中患者的血尿酸水平与预后的关系

The relationship between level of uric acid and prognosis in patients with acute ischemic stroke

目的探讨急性缺血性卒中患者血尿酸水平与预后的关系。方法选取381例发病在72h内的缺血性卒中患者,观察血尿酸水平、临床表现及预后等,并对相关资料进行统计研究。结果发现血液中尿酸的浓度与患者的预后密切相关,病初尿酸浓度越高,预后越好。结论尿酸是一种强抗氧化剂,可以为急性缺血性卒中患者脑损伤提供某种程度的保护作用。

Objective To investigate the relationship between level of uric acid and prognosis in patients with acute ischemic stroke.Methods 381 patients with acute ischemic stroke and hospitalized within 72 hours attended this study. Level of blood uric acid was measured.Clinical manifestations and prognosis were also studied.The data were analyzed by SPSS software.Results There was positive relationship between the concentration of blood uric acid and prognosis of the patients.Patients with higher level of uric acid had better prognosis.Conclusion Uric acid is one of the anti-oxidants which can provide some kind of protection against ischemic damage in acute stroke.