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滚环扩增体系及其应用研究进展 被引量:4

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摘要 该文对新近发展起来的恒温核酸扩增技术中的滚环核酸扩增技术及其应用研究进展进行介绍。滚环扩增技术是借鉴病原生物体的滚环复制方式而提出的 ,它是一种多引物的指数的体外核酸扩增技术。不仅能直接扩增特定的DNA、RNA分子 ,而且能实现这些靶核酸的信号放大 ,其灵敏度能达到 1个拷贝的核酸分子。滚环扩增技术在核酸测序、单核苷酸多态性基因分型及细胞原位检测分析、DNA芯片。
出处 《临床输血与检验》 CAS 2005年第1期73-75,共3页 Journal of Clinical Transfusion and Laboratory Medicine
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