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STAT3在小鼠胚胎肝脏的表达 被引量：4

The expression of STAT3 in mouse's embryonic liver
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摘要 目的　探讨STAT3在胚胎肝脏发育中的作用。方法　应用免疫组化技术观察STAT3在小鼠胚胎肝脏中期发育中的表达。结果　STAT3蛋白在E13.5d鼠胚肝脏中出现较强表达 ;在E14 .5d和E15 .5d鼠胚肝脏中的表达有所下降。结论　STAT3可能参与了胚胎肝脏中期发育的调控 ,并可能涉及胚胎肝脏的造血功能。 Objective To investigate the roles of STAT3 during developing mouse fetal liver by detecting the expression of STAT3 in the murine fetal liver. Methods The expression of STAT3 protein in the mid stage of the developing mouse fetal liver by using immunocytochemistry and immunofluorescence. Results There was strong positive expression of STAT3 protein in fetal liver at embryonic 13.5 day. From embryonic14.5 to 15.5 day the expression of STAT3 protein was reduced. Conclusions STAT3 protein might be participated in the development of the murine embryonic liver, as well as involved in the hematopoietic function of fetal liver.
作者 马路 李泽桂 纪华 丁震宇 星懿展
机构地区 重庆医科大学第一附属医院解剖教研室 第三军医大学组胚教研室
出处 《消化外科》 CSCD 2005年第1期52-54,共3页 Journal of Digestive Surgery
基金 国家自然科学基金资助项目 (No .3 0 170 983 )
关键词 肝脏 发育 STAT3 liver development STAT3
分类号 R329 [医药卫生—人体解剖和组织胚胎学]
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参考文献10

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二级参考文献28

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消化外科
2005年 第1期

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