摘要
血管紧张素转换酶抑制剂(ACEI)是重要的抗高血压药物之一,很多证据表明,ACEI除具有降血压作用外,对心脑血管还具有重要的保护作用,可以预防中风发生。本文通过检索MEDLINE数据库和Cochrane图书馆光盘数据库的随机对照试验和系统评价,评价ACEI类药物预防脑卒中的机制和在脑卒中防治中的作用,为临床实践提供循证医学的最佳证据。
Angiotensin converting enzyme inhibitor (ACEI) is an important type of antihypertensive drug. Much evidence shows that ACEI not only decreases the blood pressure but also has the protective effect on the cardiac and cerebral vessels. ACEI may prevent the stroke. To provide the best evidence for the clinical practice, we electronically searched RCTs and systematic reviews from MEDLINE and The Cochrane Library to evaluate the mechanisms and the effects of ACEI in stroke treatment and prevention.
出处
《中国循证医学杂志》
CSCD
2005年第1期62-66,共5页
Chinese Journal of Evidence-based Medicine
关键词
血管紧张素转换酶抑制剂
脑卒中
循证医学
Angiotensin converting enzyme inhibitors
Stroke
Evidence-based medicine