摘要
以外观、溶出度、有关物质为指标,对盐酸米多君片的处方进行筛选。结果显示采用甘露醇、预胶化淀粉、羧甲淀粉钠为主要辅料,可消除配伍禁忌,且片剂稳定性好。
The formulation of midodrine hydrochloridetablets wasoptimized using appearance,dissolution and related substancesas indexes. The resultsshowed thatmidodrinehydrochloridetabletsprepared using mannitol,pregelatinized starch and sodium carboxymethylstarch as the main excipientswere preferable.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
2005年第1期27-28,共2页
Chinese Journal of Pharmaceuticals
关键词
盐酸米多君
配伍禁忌
稳定性
midodrinehydrochloride
incompatibility
stability
