摘要
[目的]观察安心颗粒(主要由人参、桂枝、瓜蒌皮、水蛭、茯苓等中药组成)对实验性家兔高脂血症的防治作用。[方法]将32只健康雄性新西兰白兔随机分为4组,即正常对照组、模型组、脂必妥组和安心颗粒组,分别给予普通饲料、高脂饲料、高脂饲料加脂必妥片(0.156 g·kg-1·d-1)、高脂饲料加安心颗粒(0.231 g·kg-1·d-1)喂饲。10周后,测定各组动物血清总胆固醇(TC)、甘油三酯(TC)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、脂质过氧化物丙二醛(MDA)和超氧化物歧化酶(SOD)水平。[结果]安心颗粒可降低高脂血症新西兰白兔血清TC、TG、LDL-C、MDA的水平。[结论]安心颗粒能调节血脂代谢,对防治高脂血症和动脉硬化具有良好的作用。
[Objective] To observe the preventive and therapeutic effect of Anxin Granules in the treatment of hyperlipidemia [Methods] Thirty - two New Zealand male rabbits were randomized into 4 groups. Groups A, B, C and D were given with common forage, high fat forage, high fat forage with Zhibituo Tablets, high fat forage with Anxin Granules respectively. After 10 weeks of treatment, serum levels of total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol ( LDL-C), high-density lipoprotein cholesterol (HDL-C) and malondialdehyde ( MDA) and activity of superoxide dismustase (SOD) were detected. [ Results ] Anxin Granules decreased the serum levels of TC, TG, LDL-C and MDA. [Conclusion] Anxin Granules has a good effect in preventing and treating hyperlipidemia and atherosclerosis by regulating blood lipid metabolism.
出处
《广州中医药大学学报》
CAS
2005年第1期46-48,52,共4页
Journal of Guangzhou University of Traditional Chinese Medicine