1Wei MH,Popescu NC,Lerman MI,et al.Localization of the human vascular endothelial growth factor gene,VEGF,at chromosome 6p12 [J].Hum Genet,1996,97(6):794-797.
2Leung DW,Cachianes G,Kuang WJ,et al.Vascular endothelial growth factor is a secreted angiogenic mitogen [J].Science,1989,246(4935):1306-1309.
3Schmidt NO,Westphal M,Hagel C,et al.Levels of vascular endothelial growth factor,hepatocyte growth factor/scatter factor and basic fibroblast growth factor in human gliomas and their relation to angiogenesis [J].Int J Cancer,1999,84(1):10-18.
4Cheng SY,Nagane M,Huang HS,et al.Intracerebral tumor-associated hemorrhage caused by overexpression of the vascular endothelial growth factor isoforms VEGF121 and VEGF165 but not VEGF189 [J].Proc Natl Acad Sci USA,1997,94(22):12081-12087.
5Benjamin LE,Golijanin D,Itin A,et al.Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal [J].J Clin Invest,1999,103(2):159-165.
6Senger DR,Perruzzi CA,Streit M,et al.The alpha(1)beta(1) and alpha(2)beta(1) integrins provide critical support for vascular endothelial growth factor signaling,endothelial cell migration,and tumor angiogenesis [J].Am J Pathol,2002,160(1):195-204.
7Nor JE,Christensen J,Mooney DJ,et al.Vascular endothelial growth factor (VEGF)-mediated angiogenesis is associated with enhanced endothelial cell survival and induction of Bcl-2 expression [J].Am J Pathol,1999,154(2):375-384.
8Marti HH,Risau W.Systemic hypoxia changes the organ-specific distribution of vascular endothelial growth factor and its receptors [J].Proc Natl Acad Sci USA,1998,95(26):15809-15814.
9Fukumura D,Xu L,Chen Y,et al.Hypoxia and acidosis independently up-regulate vascular endothelial growth factor transcription in brain tumors in vivo [J].Cancer Res,2001,61(16):6020-6024.
10Levy NS,Chung S,Furneaux H,et al.Hypoxic stabilization of vascular endothelial growth factor mRNA by the RNA-binding protein HuR [J].J Biol Chem,1998,273(11):6417-6423.