经皮附睾精子抽吸术和睾丸精子获取术在无精子症诊断和治疗中的应用

Application of Percutaneous Epididymal Sperm Aspiration and Testicular Sperm Extraction to the Diagnosis and Treatment of Azoospermia

目的 :研究附睾和睾丸精子抽吸术对无精子症患者的诊断和治疗价值。 方法 :应用经皮附睾精子抽吸术(PESA)和睾丸精子获取术 (TESE)两种方法对 385例无精子症患者进行穿刺检查。 结果 :其中 6 4例附睾中存在精子 (1 6 .6 2 %) ;4 5例患者睾丸中存在精子 (1 1 .6 9%) ;对其中 6 4例睾丸或附睾中发现精子的患者采取PESA或TESE取精后行卵细胞胞质内单精子注射 (ICSI)治疗。胚胎移植后妊娠率为 39.0 7%。 结论 :PESA和TESE为部分无精子症患者提供了生育的机会 ,也是针对无精子症的有效的治疗手段。

Objective: To evaluate percutaneous epididymal sperm aspiration (PESA) and testicular sperm extraction (TESE) in the diagnosis and treatment of azoospermia. Methods: We examined 385 azoospermia patients using the techniques of PESA and TESE. Results: Of the total number of the azoospermia patients, 64( 16.62%) had sperm in the epididymis and 45( 11.69%)in the testis. Intracytoplasmic sperm injection (ICSI) was applied to 64 of the patients with sperm in the epididymis or testis. The pregnancy rate after the embryo transfer was 39.07%. Conclusion: PESA and TESE, as an effective therapy for azoospermia, can further the classification of azoospermia and provide chances of procreation to azoospermia patients with partial obstruction.