摘要
经纤维支气管镜(纤支镜)或人工气道行防污染样本毛刷(PSB)采样或吸引下呼吸道分泌物(吸痰)以及血、胸水培养并结合咳痰培养法确诊下呼吸道绿脓杆菌感染65例。病死率30.6％。机体免疫功能、人工气道、感染类型、病变累及范围、菌血症均与病死率有关。药敏试验显示该菌对抗生素的耐药率为29.0％～100.0％,其中对妥布霉素、丁胺卡那霉素、庆大霉素、氯霉素、头孢去甲噻肟耐药率增加更为显著(P<0.05或P<0.01)
Sixty five cases of lower respiratory tract infection of pseudomonaa aeruginosa were diagnosed on specimens frorri protected specimen brush or from aspirated sputum via fibexobronchoscope or artificial airways and from cultures of blood, pleural effusion with expectorated sputum. The mortality was 30.6%. Immunologic functional status, use of artificial airways, routes of infection, extent of lesiona, and development of bacteremia were related to mortality. Drug susceptibility tests showed that resistance rate was 29.0%-100.0%, among them tobramycin, gentamicin, ceftazidime and amikacin were 29.0%, 34.4%, 36.4% and 38.1%, respectively. Drug resistance rate was increased significantly in recent three years especially to tobramycin, amikacin, gentamicin, chloramphenicol, ceftizoxime.
出处
《上海医科大学学报》
CSCD
1993年第1期26-30,共5页
Journal of Fudan University(Medical Science)
关键词
下呼吸道
感染
绿脓杆菌
lower respiratory tract
infection
pseudomonas aeruginosa
