面包酵母细胞循环模型的实验验证

Verification of the Cell Cycling Model for Baker’s Yeast

本文对作者早期提出的面包酵母细胞循环模型CCM进行了改进和动态实验验证。结果表明,CCM的动态特性基本与真实过程相符。基于该模型设计的酵母流加发酵最优进料控制策略的实施结果证实,CCM能够用于酵母生产的质量控制。

The cell cycling model (CCM) for baker's yeast Sachromyces cerevisiae proposed earlier was modified and dynamically verified with our own experiments. It was shown that the simulations by the modified CCM are coincident with the experimental data. Based on the CCM, optimal feeding strategy in a fed-batch culture for baker's yeast was designed to minimize the fraction of budding cells (FBC)in cell population so as to enhance the fermentation activity of yeast product. The optimal control experiment was carried out with very successful results.