口腔颌面部海绵状血管瘤注射治疗的对比研究

Comparative study of effects of pinyangmycin and sodium morrhuate injection on cavernous hemangioma in maxillofacial regions

目的 比较平阳霉素和鱼肝油酸钠注射治疗口腔颌面部海绵状血管瘤的疗效 ,探求治疗口腔颌面部海绵状血管瘤的理想方法。方法 用平阳霉素加地塞米松和鱼肝油酸钠分别行血管瘤腔内注射 ,治疗口腔颌面部海绵状血管瘤各 2 8例 ,对比分析两组的疗效。结果 两组的有效率均为 10 0 % ,平阳霉素组的治愈率为82 1% ,鱼肝油酸钠组的治愈率为 5 7 1% ,两组治愈率差异有显著性 (P <0 0 5 )。结论 :平阳霉素加地塞米松治疗口腔颌面部海绵状血管瘤的疗效优于鱼肝油酸钠 ,而且副作用小 ,无复发 。

Objective To compare the effects of local injected pinyangmycin with sodium morrhuate on cavernous hemangioma in maxillofacial regions and to investigate an ideal method to treat cavenous hemangioma of maxillofacial regions.Method 56 patients with cavernous hemangioma of maxillofacial regions who were treated in our hospital from 1992 to 2000 were reviewed. 28 patients were locally injected with pinyangmycin and dexamethasonum, and the other 28 patients were treated with sodium morrhuate, and the effects of these two groups were compared.Result The response rates of both groups were 100%. The healing rate of pinyangmycin and dexamethasonum was 82.1% and that of sodium morrhuate was 57.1%. There were significant differences between the healing rates of these two groups(P<0.05).Conclusion The effect of pinyangmycin and dexamethasonum on cavernous hemangioma of maxillofacial regions was better than that of sodium morrhuate. This method may be a safe, simple and effective therapy that has little side effect to cavernous hemangioma of maxillofacial regions.