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Relationship between metabolic syndrome and erectile dysfunction 被引量:2

Relationship between metabolic syndrome and erectile dysfunction
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摘要 Aim: To determine the relationship between metabolic syndrome (MS) and erectile dysfunction (ED) and to see which risk factors correlated the best with ED. Methods: Seventy-nine cardiology clinic outpatients with coronary artery disease (CAD) and lipid metabolism disorder were recruited. They were categorized as having MS, hypertension (blood pressure greater than 130/85 mmHg) and dyslipidemia. ED was classified based on International Index of Erectile Function scores. Patients were grouped into quartiles based on body mass index (BMI). Chi-square, Pearson's correlation and regression tests were used for statistical analysis. Results: The mean age of the patients was 56.6 years. ED was diagnosed in 59 (74.7 %) of the 79 patients. In the 38 patients with MS, all had ED. ED was not significantly correlated with cholesterol levels (P > 0.05), but was found often in patients who had both hyperc-holesterolemia and HT (P<0.01). Nineteen(76 %) of the 25 patients who had dyslipidemia had ED. However, ED was not significantly correlated with dyslipidemia (P > 0.05). Tweenty-two of the 23 patients who had BMI greater than 30 had ED, which was significantly more prevalent than that in those who had normal BMI (P<0.01). ED was seen in 38 of 53 smoker patients. Although ED was more prevalent in cigarette smokers, it was not significantly different from non-smokers (P>0.5). Conclusion: ED is present in a high percentage of patients with MS. Among multiple risk factors for ED, MS correlates the most highly. The next most important risk group is the patients with hypertension +hypercholestrolemia and obesity (BMI > 30). Aim: To determine the relationship between metabolic syndrome (MS) and erectile dysfunction (ED) and to see which risk factors correlated the best with ED. Methods: Seventy-nine cardiology clinic outpatients with coronary artery disease (CAD) and lipid metabolism disorder were recruited. They were categorized as having MS, hypertension (blood pressure greater than 130/85 mmHg) and dyslipidemia. ED was classified based on International Index of Erectile Function scores. Patients were grouped into quartiles based on body mass index (BMI). Chi-square, Pearson's correlation and regression tests were used for statistical analysis. Results: The mean age of the patients was 56.6 years. ED was diagnosed in 59 (74.7 %) of the 79 patients. In the 38 patients with MS, all had ED. ED was not significantly correlated with cholesterol levels (P > 0.05), but was found often in patients who had both hyperc-holesterolemia and HT (P<0.01). Nineteen(76 %) of the 25 patients who had dyslipidemia had ED. However, ED was not significantly correlated with dyslipidemia (P > 0.05). Tweenty-two of the 23 patients who had BMI greater than 30 had ED, which was significantly more prevalent than that in those who had normal BMI (P<0.01). ED was seen in 38 of 53 smoker patients. Although ED was more prevalent in cigarette smokers, it was not significantly different from non-smokers (P>0.5). Conclusion: ED is present in a high percentage of patients with MS. Among multiple risk factors for ED, MS correlates the most highly. The next most important risk group is the patients with hypertension +hypercholestrolemia and obesity (BMI > 30).
机构地区 Department of Urology
出处 《Asian Journal of Andrology》 SCIE CAS CSCD 2004年第4期355-358,共4页 亚洲男性学杂志(英文版)
关键词 erectile dysfunction metabolic syndrome DYSLIPIDEMIA body mass index erectile dysfunction metabolic syndrome dyslipidemia body mass index
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参考文献10

  • 1Jeremy JY,Mikhailidis DP.Cigarette smoking and erectile dysfunction[].The Journal of The Royal Society for The Promotion of Health.1998
  • 2Walczak MK,Lokhandwala N,Hodge MB,Guay AT.Prevalence of cardiovascular risk factors in erectile dysfunction[].Journal of Gender Specific Medicine.2002
  • 3Ford ES,Giles WH,Dietz WH.Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey[].The Journal of The American Medical Association.2002
  • 4Sulliyan ME,Thompson CS,Dashwood MR,Khan MA,Jeremy JY,Morgan RJ,et al.Nitric oxide and penile erection: is erectile dysfunction another manifestation of vascular disease[].Cardiovascular Research.1999
  • 5Vallance P,Chan N.Endothelial function and nitric oxide: clinical relevance[].Heart.2001
  • 6Roth A,Kalter-Leibovici O,Kerbis Y,Tenenbaum-Koren E,Chen J,Sobol T,et al.Prevalence and risk factors for erectile dysfunction in men with diabetes, hypertension, or both diseases: a community survey among 1 412 Israeli men[].Clinical Cardiology.2003
  • 7Sae-Chul Kim.Hyperlipidemia and erectile dysfunction[J].Asian Journal of Andrology,2000,2(3):161-166. 被引量:6
  • 8Schachter M.Erectile dysfunction and lipid disorders[].Current Medical Research and Opinion.2000
  • 9Cohen PG.Aromatase, adiposity, aging and disease.The hypogonadal-metabolic-atherogenic-disease and agingconnection[].Medical Hypotheses.2001
  • 10Simonsen U.Interactions between drugs for erectile dysfunction and drugs for cardiovascular disease[].International Journal of Impotence Research.2002

二级参考文献11

  • 1Sae Chul Kim,In Kyu Kim,Kyung Kenn Seo,Kwang Jin Baek,Moo Yeol Lee.Involvement of superoxide radical in the impaired endothelium-dependent relaxation of cavernous smooth muscle in hypercholesterolemic rabbits[J].Urological Research.1997(5)
  • 2Schmidt HHHW,Pollock JS,Nakane M,Gorsky LD,Fostermann U,Murad F.Purification of a soluble isoform of guanylyl cyclase-activating factor synthase[].Proceedings of the National Academy of Sciences of the United States of America.1991
  • 3Kim SC,Kim IK,Seo KK,Baek K J,Lee MY.Involvement of superoxide radical in the impaired endothelium-dependent relaxation of cavernous smooth muscle in hypercholesterolemic rabbits[].Urological Research.1997
  • 4Lewis TV,Dart AM,Chin-Dusting JP.Endothelium-dependent relaxation by acetylcholine is impaired in hypertriglyceridemic humans with normal levels of plasma LDL cholesterol[].Journal of the American College of Cardiology.1999
  • 5Henriksson P,Bergstrom K,Edhag O.Experimental atherosclerosis and a possible generation of free radicals[].Thrombosis Research.1985
  • 6Kim SC,Kim IK,Lee MY,Uhm DY.Relaxation responses of cavernous smooth muscles to vasodilators in impotent patients with hypercholesterolemia or hypertriglyceridemia[].Kor J Androl.1995
  • 7Fostermann U,Pollock JS,Schmidt HHHW,Mitchell JA,Kohlhaas KL,Heller M,et al.Characterization and purification of particulate EDRF synthase from bovine aortic endothelial cells[].The FASEB Journal.1991
  • 8Kim SC,Seo KK,Kim HW,Lee MY.The effects of isolated lipoproteins and triglyceride, combined oxidized LDL plus triglyceride, and combined oxidized LDL plus HDL on the contractile and relaxation response of rabbit cavernous smooth muscle[].International Journal of Andrology.2000
  • 9Kanazawa K,Kawashima S,Mikami S,Miwa Y,Hirata K,Suematsu M,et al.Endothelial constitutive nitric oxide synthase protein and mRNA increased in rabbit atherosclerotic aorta despite impaired endothelium-dependent vascular relaxation[].American Journal of Pathology.1996
  • 10Sreeharan N,Jayakody RL,Senaratne MPJ,Thomson ABR,Kappagoda CT.Endothelium-dependent relaxation and experimental atherosclerosis in the rabbit aorta[].Canadian Journal of Physiology and Pharmacology.1986

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