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周期性瘫痪患者血清肌酶改变及其临床意义 被引量:5

Changes of serum creatase and its clinical significance in patients with periodic paralysis
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摘要 目的 探讨周期性瘫痪患者发作期肌酶改变及其临床意义。方法 用速率法检测 10 3例周期性瘫痪患者发作期及 35名健康对照者的血清肌酸磷酸激酶 (CPK)、乳酸脱氢酶 (LDH)及天门冬氨酸氨基转移酶 (AST) ,分析肌酶改变与临床的关系。结果 患者各种血清肌酶水平与对照组比较均有显著升高 (均P <0 0 1) ;血清肌酶水平与临床肌力、伴发肌肉酸痛及症状持续时间有关。 Objective To study the changes of serum creatase and its clinical significance in patients with periodic paralysis.Methods The serum creatine phosphatase (CPK),lactate dehydrogenase (LDH) and aspartate aminotransferase (AST) were measured by means of speed rate method in 103 patients of periodic paralysis and 35 healthy persons as the control group. The relationship between increased serum creatase levels and the clinic findings was analyzed.Results Compared with the controls, all kinds of serum creatase levels in the patients elevated in different levels, and the differences were significant (all P<0.01). Serum creatase levels were related to muscle power, muscular soreness and the lasting time of clinic signs.Conclusion The levels of elevated creatase and muscular soreness may serve as an indication of predicting development and prognosis in periodic paralysis.
出处 《临床神经病学杂志》 CAS 2004年第6期422-423,共2页 Journal of Clinical Neurology
关键词 周期性瘫痪 血清肌酶 periodic paralysis serum creatase
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