C-反应蛋白在急性冠状动脉综合征中的应用价值

The Applicative Value of C-reactive Protein in Acute Coronary Artery Syndrome

目的 探讨C 反应蛋白在急性冠状动脉综合征中的应用价值。方法 分别检测稳定型心绞痛 3 6例 ,不稳定型心绞痛 2 4例 ,急性心肌梗死急性期 (1个月内 ) 5 7例 ,急性心肌梗死恢复期 (1年内 ) 44例及 5 9名健康人的C 反应蛋白。结果 急性心肌梗死急性期与不稳定型心绞痛分别为 (19 2 2± 13 0 3 )mg/L和 (15 47± 12 61)mg/L ,与对照组 (3 63± 2 5 9)mg/L相比 ,差异非常显著 (P <0 0 1)而稳定型心绞痛 [(4 .2 4± 5 .3 0 )mg/L]与急性心肌梗死恢复期 [(6 0 3± 8 43 )mg/L]与对照组比较 ,无显著差异 (P均 >0 0 5 )。结论 C 反应蛋白作为急性心肌梗死和不稳定型心绞痛的预报因子是敏感和可靠的。

Objective To investigate the applicative value of C-reactive protein in acute coronary syndrome.Methods Serum C-reactive protein (CRP) concentrations were measured respectively in 36 patient with stable angina pectoris (SAP), 24 patients with unstable angina pectoris (UAP), 57 patients with acute myocardial infarction (AMI) who were within acute phase (shorter than a month), 44 patients with acute myocardial infarction who were in recovery period and 59 healthy controls.Results he concentrations of serum CRP were significantly higher in acute phase of AMI \ and UAP \ than in healthy controls \ (P<0.01). There was no significant difference in serum CRP concentration between SAP \ or recovery period AMI \ and healthy controls. Conclusion C-reactive protein can be used as a sensitive and reliable predictor for AMI and UAP.