生长抑素治疗肝癌的机制及其临床应用
摘要
近年的研究表明用生长抑素 (SS)治疗肝癌等实体瘤具有潜在的应用前景。本文就SS治疗肝癌的作用机制及其临床应用作一综述。
出处
《汕头大学医学院学报》
2004年第4期240-242,共3页
Journal of Shantou University Medical College
参考文献28
-
1Patel YC,Srikant CB.Subtype selectivity of peptide analogs for all five cloned human somatostatin receptors(hsstr1-5)[J].Endocrinology,1994,135(6):2814-2817.
-
2Fiebiger WC,Scheithauer W,Traub T,et al.Absence of therapeutic efficacy of the somatostatin analogue lanreotide in advanced primary hepatic cholangiocellular cancer and adenocarcinoma of the gallbladder despite in vivo somatostatin-receptor expression[J].Scand J Gastroenterol,2002,37:222-225.
-
3Dimitroulopoulos D,Xinopoulos D,Tsamakidis K,et al.The role of sandostatin LAR in treating patients with advanced hepatocellular cancer[J].Hepatogastroenterology,2002,49:1245-1250.
-
4Kouroumalis E,Skordilis P,Thermos K,et al.Treatment of hepatocellular carcinoma with octreotide:a randomised controlled study[J].Gut,1998,42:442-447.
-
5Eden PA,Taylor JE.Somatostatin receptor subtype gene expression in human and rodent tumors[J].Life Sci,1993,53: 85-90.
-
6Reubi JC,Zimmermann A,Jonas S,et al.Regulatory peptide receptors in human hepatocellular carcinomas[J].Gut,1999,45:766-774.
-
7颜登国,区庆嘉.生长抑素受体亚型SSTR-2和SSTR-3mRNA在原发性肝癌中的表达[J].癌症,2001,20(2):152-155. 被引量:14
-
8刘建生,彭淑牖,吴育莲,彭承宏,陈怀增,Gao YY.人类生长抑素受体mRNA在原发性肝癌中的表达[J].中华消化杂志,2002,22(11):683-683. 被引量:6
-
9Bruno JF,Xu Y.Tissue distribution of somatostatin receptor subtype messenger robonucleic acid in the rat[J].Endocrinology,1993,33:2561-2567.
-
10Theveniau MA,Yasuda K,Bell GI,et al.Immunological detection of isomorfs of the somatostatin receptor Subtype,SSTR2[J].F Neruochem,1994,63:447-455.
二级参考文献20
-
1杨继金,朱永法.大白鼠转移性肝癌模型的制作[J].中华放射学杂志,1993,27(2):122-123. 被引量:42
-
2Thangaraju M,Cancer Res,1999年,59卷,1649页
-
3Bonin S, Pascolo L, Croce LS, et al. Gene expression of ABC proteins in hepatocellular carcinoma, perineoplastic tissue, and liver diseases. Mol Med, 2002, 8:318-325.
-
4Nies AT, Konig J, Pfannschmidt M, et al. Expression of the multidrug resistance proteins MRP2 and MRP3 in human hepatocellular carcinoma. Iht J Cancer, 2001, 15: 94:492-499.
-
5Romani R, Morris DL. SMS 201. 995 Sandostatin enhances in-vitro effects of 5-fluorouracil in colorectal cancer. Eur J Surg Oncol,1995,21:27-32.
-
6Szende B, Horvath A, Bokonyi G, et al. Effect of a novel somatostatin analogue combined with cytotoxic drugs on human tumour xenografts and metastasis of B16 melanoma. Br J Cancer, 2003,88:132-136.
-
7SchallyAV.Oncologicalapplicationsofsomatostatinanalogus[J][].CancerRes.1988
-
8StevenWJ,AartJanDL,WouterWDetal.Drugtherapy:Octreotide[J][].TheNewEnglandJournalofMedicine.1996
-
9KouroumalisE,SkordilisP,ThermosKetal.Treatmentofhepatocellularcarcinomawithoctreotide:arandomisedcontrolledstudy[J][].Gut.1998
-
10KubotaA,YamadaY,KagimotoSetal.IdentificationofsomatostatinreceptorsubtypesandanimplicationfortheefficacyofsomatostatinanalogueSMS201995intreatmentofhumanendocrinetumors[J][].JofClinInvest.1994
共引文献78
-
1张宪峰,李恒力,窦剑,邢宏利,李新国,闫广智,鲍鸿斌.射频消融联合奥曲肽治疗邻近大血管肝癌的临床研究[J].中华临床医师杂志(电子版),2011,5(10):2911-2913. 被引量:2
-
2李姗霓,孙丽莹.肝细胞肝癌中生长抑素受体2/5的表达研究[J].实用器官移植电子杂志,2013,1(2):107-111. 被引量:1
-
3Effect of octreotide on angiogenesis induced by hepatocellular carcinoma in vivo[J].Hepatobiliary & Pancreatic Diseases International,2003,2(3):404-409. 被引量:2
-
4李煜,李建生,许戈良,傅斌生,徐师国,张友久.BEL-7402肝癌细胞株的生长抑素受体放射分析[J].安徽医科大学学报,2004,39(3):196-198.
-
5张卫国,吴清明,王小虎,谢国建,刘先军,王强.奥曲肽对食管癌细胞DNA合成及端粒酶活性的影响[J].江苏医药,2004,30(7):525-526.
-
6王涌,彭承宏,刘颖斌,刘宏,赵之明,韩宝三.奥曲肽联合肝动脉栓塞化疗预防肝癌术后复发转移的临床研究[J].中华肝胆外科杂志,2004,10(9):594-596. 被引量:5
-
7Hai-linLIU LiHUO LeiWANG.Octreotide inhibits proliferation and induces apoptosis of hepatocellular carcinoma cells[J].Acta Pharmacologica Sinica,2004,25(10):1380-1386. 被引量:15
-
8叶红,但自力,唐望先.全反式维甲酸联合奥曲肽对肝癌细胞-HepG_2增生和凋亡的影响[J].世界华人消化杂志,2004,12(10):2295-2298. 被引量:3
-
9许戈良,傅斌生,徐荣楠.生长抑素对人肝癌细胞株BEL-7402血管内皮生长因子表达与合成的影响[J].中华外科杂志,2004,42(24):1526-1528. 被引量:4
-
10冒海蕾,黄介飞,倪润洲,魏群,张弘,肖明兵,江枫,谭兵,李峰.奥曲肽对大鼠原发性肝细胞癌抗肿瘤作用的实验研究[J].南通大学学报(医学版),2005,25(1):30-33. 被引量:1
-
1鲍春燕,胡志雯.表皮生长因子受体抑制剂治疗实体瘤发生皮肤不良反应的护理[J].中国社区医师(医学专业),2009,11(23):236-236.
-
2Hannoud S.,Rixe O.,Bloch J.,李晓莉.与表皮生长因子抑制剂相关的皮肤体征(法语)[J].世界核心医学期刊文摘(皮肤病学分册),2006,0(10):32-33.
-
3周淑华,林麟.Sweet综合征的临床研究进展[J].中华皮肤科杂志,2001,34(4):314-315. 被引量:7
-
4陆惠清,梁珑.超声引导,醋酸治疗肝癌及临床护理[J].抗癌,2005(1):35-36.
-
5许轶琛,朱世杰.李佩文治疗肝癌经验简介[J].北京中医药,2008,27(6):427-428. 被引量:7
-
6凌兰兰,陈月,于亮.造血干细胞移植治疗银屑病研究进展[J].中国综合临床,2016,32(5):475-478. 被引量:2
-
7杨绍杰.CHR-2797的临床试验开始[J].国外药讯,2005(2):19-19.
-
8方晓芬,赵磊,吕宇克.周维顺应用四逆散加减治疗肝癌经验[J].浙江中西医结合杂志,2010,20(7):414-414. 被引量:3
-
9张令海.超声引导下冷循环射频治疗肝癌41例探讨[J].上海医学影像,2003,12(3):214-215. 被引量:1
-
10喻燕敏,吴丽萍.体部伽玛刀治疗肝癌的护理[J].世界肿瘤杂志,2004,3(3):299-300. 被引量:1