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瘦素和肥胖相关性高血压 被引量：1

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摘要 动物试验和临床研究等表明瘦素与高血压存在一定的联系。肥胖者往往存在瘦素抵抗 ,此种抵抗发生于调节代谢的作用而不是兴奋交感神经的作用。瘦素通过交感神经系统、一氧化氮等调节血管张力和血压 ,在肥胖相关性高血压的发病机制中起着重要作用。
作者 刘国强(综述) 曾正陪(审校)
机构地区 中国医学科学院
出处 《国外医学（内分泌学分册）》 2005年第1期61-63,共3页 Foreign Medical Sciences(Section of Endocrinology)
关键词 瘦素 肥胖 高血压 动物试验 发病机制
分类号 R589.2 [医药卫生—内分泌] R544.1 [医药卫生—心血管疾病]
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参考文献26

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  • 2Carlyle M, Jones OB, Kuo J, et al. Chronic cardiovascular and renal actions of leptin: role of adrenergic activity. Hypertension, 2002, 39:496-501.
  • 3Rahmouni K, Haynes WG, Morgan DA, et al. Selective resistance to central neural administration of leptin in agouti obese mice. Hypertension, 2002,39: 486-490.
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  • 7黎明,吴从愿,詹志伟,杨静,张葵,李晓光,甘利虹,纪宝华.血清瘦素水平与原发性高血压的相关性研究[J].中华医学杂志,2003,83(12):1058-1061. 被引量：31
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二级参考文献14

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  • 10Mark AL, Correia ML, Rahmouni K, et al. Selective leptin resistance: a new concept in leptin physiology with cardiovascular implications. J Hypertens, 2002, 20: 1245-1250.

共引文献30

同被引文献28

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二级引证文献3

国外医学（内分泌学分册）
2005年 第1期

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