复发性口腔溃疡与消化道疾病相关性的流行病学调查

Survey and analysis of subjects with recurrent aphthous stomatitis and peptic diseases

目的:调查了解消化道疾病患者复发性口腔溃疡 (RAU)的发病情况,为口腔溃疡的防治提供参考依据.方法: 对南方医院胃肠镜室246例就诊的消化道疾病患者,进行了 口腔溃疡发病与消化道疾病相关性的调查分析.结果:所收 集的246例患者中,慢性浅表性胃炎163例,占66.3%(163 246);胃、十二指肠溃疡(PU)83例,占33.7%(83/246).在 246例患者中103例诊断出患有RAU,占41.9%.在163例胃 炎中67例伴发RAU,占41.1%;在83例PU中36例患者伴 发RAU,占43.4%.χ2检验统计数据结果表明,胃炎和PU的 RAU发病率无显著差异性(P>0.05);RAU在消化道疾病患 者中的发病率与健康人群RAU的发病率之间有显著差异 (P<0.01).结论:消化道疾病患者RAU发病率高于健康人 群RAU的发病率,表明消化道疾病与RAU的发病之间存在 关联.

AIM: To investigate the distribution and diagnosis of recurrent aphthous stomatitis (RAU) for better prevention and treatment. METHODS: The distribution and diagnosis of 246 patients in Outpatient Department were surveyed and analyzed. RESULTS: The RAU rate of the 246 patients was 41.9% (103/246), among whom the RAU rate of the 163 patients with gastritis was 41.1%(67/163)and the RAU rate of the 83 patients with peptic ulcer (PU) was 43.4% (36/83). No significant difference was found between the RAU rate of patients with gastritis and that of patients with PU (P>0.05) while significant difference was found between the RAU rate of healthy control and that of patients with digestive diseases. CONCLUSION: The results show that the RAU rate is significantly higher in people with digestive diseases, indicating that RAU is related to digestive diseases.