期刊文献+

TAE方案治疗难治性急性非淋巴细胞白血病疗效观察

下载PDF
导出
摘要 目的 观察TAE方案对难治性急性非淋巴细胞白血病的疗效。方法 选择 2 1例难治性急性非淋巴细胞白血病应用TAE方案治疗作为治疗组 ,选择同期应用其他方案化疗的难治性急性非淋巴细胞白血病 2 4例作为对照组 ,观察其疗效及不良反应 ,并进行比较。结果 治疗组化疗后完全缓解率及总有效率均明显高于对照组 (P <0 0 5 )。结论 TAE方案治疗难治性急性非淋巴细胞白血病有明确的疗效 ,是治疗难治性急性非淋巴细胞白血病较好的方案。
作者 魏磊 张健
出处 《济宁医学院学报》 2004年第4期43-43,共1页 Journal of Jining Medical University
  • 相关文献

参考文献3

  • 1陈协群,万幼峰,白庆咸,曹云新.拓扑异构酶Ⅰ抑制剂对K562细胞的杀伤与诱导凋亡作用[J].癌症,2002,21(4):356-359. 被引量:13
  • 2Ester E H,Thall P F,Cortes J E,et al. Comparison of idarubicin + ara -C,fludarabine + ara- C,and topotevan + ara- C based regimens in treatment of newly diagnosed acute myeloid leukemia, refractory anemia with excess blasts. Blood,2001,98: 3575
  • 3Lee S T,Jang J H, Suh H C,et al. Idarubicin,cytarabine, and topotecan in patients with refractory or relapsed acute myelogenous leukemia and high- risk myelodyplastic syndrome. Am J Hematol, 2001,68:237

二级参考文献10

  • 1Kantarjian HM,Giles FJ,O Brien SM,et al.Clinical course and therapy of chronic myelogenous leukemia with interferon alpha and chemotherapy [J].Hematol Oncol Clin North Am,1998,12:31- 80.
  • 2Seiter K,Feldman EJ,Halicka HD,et al.Phase I clinical and laboratory evaluation of topotecan and cytarabine in patients with acute leukemia [J].J Clin Oncol,1997,15:44- 51.
  • 3Park SJ,Kim DW,Kim HJ,et al.Topotecan based combination chemotherapy in patients with transformed chronic myelogenous leukemia and advanced myelodysplastic syndrome [J].Korean J Intern Med,2000,15:122- 126.
  • 4Eischen CM,Kottke TJ,Martins LM,et al.Comparison of apoptosis in wild type and Fas resistant cells:chemotherapy induced apoptosis is not dependent on Fas/Fas ligand interactions [J].Blood,1997,90:935- 943.
  • 5Fadok VA,Voelker DR,Campbell PA,et al.Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages [J].J Immunol,1992,148:2207- 2216.
  • 6Koopman G,Reutelingsperger CP,Kuijten GA,et al.Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis [J].Blood,1994,84:1415- 1420.
  • 7Seiter K.Induction of apoptosis by topotecan:implications for the treatment of leukemia [J].Semin Hematol,1998,35(3suppl 4):22- 25.
  • 8Wickremasinghe RG,Hoffbrand AV.Biochemical and genetic control of apoptosis:Relevance to normal hematopoiesis and hematological malignancies [J].Blood,1999,93:3587.
  • 9Hengartner MO.The biochemistry of apoptosis [J].Nature,2000,407:770- 775.
  • 10Wesselborg S,Engels IH,Rossmann E,et al.Anticancer drugs induce caspase 8/FLICE activation and apoptosis in the absence of CD95 receptor/ligand interaction [J].Blood,1999,93:3053-3060.

共引文献12

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部