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CD44基因在非小细胞肺癌患者纵隔淋巴结和肺癌组织中表达的定量分析 被引量:1

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摘要 目的研究CD44基因表达与肺癌术后复发的关系,探讨逆转录聚合酶链反应法评判临床病情演变及预后的可行性。方法采用逆转录聚合酶链反应法,检测与肿瘤发生和转移密切相关的CD44基因在46例非小细胞肺癌患者手术切除的病理标本中的异常表达情况,结合临床及病理分型和5年随访结果进行观察研究。结果CD44基因在肺癌组织和纵隔组织过量表达与肺癌术后复发及5年生存率密切相关。结论逆转录聚合酶链反应法检测CD44基因表达可作为评判肺癌患者术后复发及转移的预测指标。
出处 《中国综合临床》 北大核心 2005年第2期171-172,共2页 Clinical Medicine of China
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