摘要
RNA沉默是真核生物中普遍存在的抵抗病毒复制表达、抑制转座子转座及调控基因表达的监控机制。植物中的RNA沉默 (转录水平的基因沉默PTGS)在RdRP的作用、transitiveRNAi的双向延伸、沉默效应的系统性传播等方面与动物中有所不同 ,且植物中的内源性miRNA在数量和种类上也更具多样性。
RNA silencing is a supervising mechanism in eukaryote which can prevent virus duplication,repress transposition of transposon and regulate gene expression.Compared with that in animals,RNA silencing in plants shows some differences in the function of RdRP,in bi-directional transitive RNAi,and in systemic propagation,etc.Meanwhile,the endogenous small RNAs in plants are more diverse than those in animals.In this paper,it is reviewed of the mechanism of RNA silencing in plants and the possibility of its use in plant functional Genomics.
基金
国家 8 63项目 (编号 :2 0 0 1AA2 410 3 2 )
国家自然科学基金 (编号 :3 0 3 70 85 7)~~