Restoration of baroreflex function by ketanserin is not blood pressure dependent in conscious freely moving rats

Objective: Since the end of the 1980s,the pathological importance of baroreflex function has attracted the attention of many investigators. In our previous studies, it was found that ketanserin lowered blood pressure(lAP), decreased BP variability and enhanced baroreflex sensitivity(BRS). The present work was designed to test the hypothesis that the restoration of BRS by ketanserin is not dependent on lAP level in conscious rats.