雌三醇栓经阴道用药对灼口综合征的临床治疗分析

The clinical analysis of intravaginal estrin suppository on burning mouth syndrome

目的观察经阴道给予雌激素后对灼口综合征的疗效。方法采用甲硝唑栓(对照组)和雌激素栓(雌三醇栓,E3栓剂,治疗组)分别经阴道用药,并对甲硝唑栓组行自身前后对照。结果甲硝唑使用后对灼口综合征无效,自身前后对照有统计学意义;雌三醇栓组与甲硝唑组相比较具有统计学意义。结论应用雌三醇栓剂可作为治疗灼口综合征的有效手段,在治疗灼口综合征的同时明显地改善了更年期的症状,收到了一举两得的效果,其疗效肯定,使用简单,方便,长期使用对机体无不良刺激。

Objective To determine the clinical effects of estnn for the treatment of burning mouth syndrome. Methods The study was divided into two groups. The control group was treated with an intravaginal metronidazole suppository. The treatment group was given an intravaginal estrin (E3) suppository. Clinical effects were compared before and after the treatments and between the two groups. Results Metronidazole suppository treatment did not show clinical effects on burning mouth syndrome. There was a significant difference in clinical effects of estrin for the treatment of burning mouth syndrome between the treatment and the control groups ( P < 0. 01). Conclusion E3 suppository is more effective in treating burning mouth syndrome. There are no significant side effects of long-term use of E3 suppository in patients.