1Rubens C ,Halank M,Wensel R,et al. Endothelin-1 and endothelin-1 plasma levels are correlated with the severity of primary pulmonary hypertension. Chest,2001,120 ( 5 ) : 1562-1569.
2Yamamoto K,Ikeda U, Mito H,et al. Endothelin production in pulmonary circulation of patients with mitral stenosis. Circulation,1994,89(5) :2093-2098.
3Channick RN, Sitbon O, Robbins I, et al. Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension : a randomised placebo-controlled study. Lancet, 2001,358(9288) :1119-1123.
4Rubin LJ, Badesch DB, Barst RJ,et al. Bosentan therapy for pulmonary arterial hypertension. N Engl J Med ,2002,346 (12) :896-903.
5Galie N, Adam T, Thierry F, et al. Effects of the oral endothelin-receptor antagonist bosentan on echocardiographic and Doppler measures in patients with pulmonary arterial hypertension. J Am Coll Cardiol,2003,41 ( 8 ) : 1380-1386.
8Yamamoto K , Ikeda U , Mito H , et al. Endothelin production in pul-monary circulation of patient with mitral stenosis [ J ]. Circulation, 1994,89 ( 5 ) :2093-2098.
9Rubens C,Halank M, Wensel R,et al. Endothelin-I and endothelin-I plasma Levels are correlated with the severity of prionary pul-monary hypertension[J]. Chest,2001,120(5) :1562-1569.
10Faulx MD, Wright AT, Hoit BD, et al. Detection of endothelial dysfunction with brachial artery ultrasound scanning [ J ]. Am Heart J 2003,145 ( 6 ) :943-960.