治疗慢性特发性荨麻疹用药方案的成本-效果分析

Cost-effectiveness Analysis of Regimens for Treatment of Chronic Idiopathic Urticaria

目的:对3种慢性特发性荨麻疹治疗方案进行成本-效果分析。方法:根据文献资料,选择96例慢性特发性荨麻疹病人,随机分为咪唑斯汀组、西替利嗪组和氯雷他定组,运用药物经济学方法对3个治疗组进行最小成本、成本-效果比及增加成本-增效比的比较分析。结果:3组疗效差异无显著性(P>0.05),西替利嗪组费用成本最低,为3组方案中最优选方案。结论:通过药物经济学方法对用药方案进行成本-效果分析,为临床治疗方案的选择提供参考。

Objective: To make cost-effectiveness analysis of 3 regimens for treatment of chronic idiopathic urticaria. Methods: On the basis of clinical data that have been published, 96 cases with chronic idiopathic urticaria were randomly divided into 3 groups, in which they were treated with mizolastine, cetirizine and loratadine respectively. The cost-effectiveness of 3 reqimens was analyzed and compared with each other by pharmacoeconomical methods. Results: There is no significant differece in the effectiveness of 3 treatment groups, however, the cost of cetirizine group was the lowest. Conclusion: The cost-effectiveness analysis of dosing regimens by pharmacoeconomical methods is helpful to select better clinical treatment.