胃癌相关蛋白GCRG213在胃癌细胞中特异性表达被引量：1

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摘要目的:观察来源于胃癌高表达基因GCRG213抗体在两种不同细胞的表达情况,评价GCRG213抗体的肿瘤特异性. 方法:应用免疫印迹方法对GCRG213抗体在胃癌细胞SGC-7901和胃上皮细胞HFE-145的表达进行比较分析. 结果:GCRG213抗体与胃癌SGC-7901细胞蛋白免疫结合后在相应大小位置有一清晰的特异性条带,而与胃上皮HFE-145细胞蛋白免疫结合后则无特异性条带出现, GCRG213抗体与两种细胞蛋白的结合存在明显差异. 结论:GCRG213抗体具有很强的肿瘤特异性.

作者王卫华吴本俨伍银桥尤纬缔

机构地区中国人民解放军总医院南楼消化科

出处《世界华人消化杂志》 CAS 北大核心 2005年第1期80-81,共2页 World Chinese Journal of Digestology

基金国家自然科学基金资助课题 No.30370635

关键词抗体肿瘤胃癌细胞特异性表达相关蛋白 GCRG213 高表达 HFE 基因免疫印迹

分类号 R735.2 [医药卫生—肿瘤] R392 [医药卫生—免疫学]

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1廉宏伟,李杰,王卫华,段晓剑,王刚石.LINE-1核酸内切酶变异体GCRG213在人正常胃黏膜的表达[J].中国老年学杂志,2014,34(8):2184-2186. 被引量：2

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